Go 6976

Name: Go 6976
SKU: A12419
Price: 490 CNY
Rating: 5 (288 reviews)

目录号: A12419

PKC 抑制剂

Go6976 是一种强效的 PKC 抑制剂，其 IC50 分别为 7.9 nM、2.3 nM 和 6.2 nM，针对 PKC (大鼠脑)、PKCα 和 PKCβ1。同时也是 JAK2 和 Flt3 的强效抑制剂。

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Grouped product items
规格	价格	库存
1mg	¥490.00	现货
5mg	¥1,225.00	现货
10mg	¥1,960.00	现货
25mg	¥3,325.00	现货
50mg	¥4,760.00	现货
100mg	¥6,650.00	现货
*10mM 1mL in DMSO**	¥1,225.00	现货
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Data Sheet

SDS

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生物活性

Discription

Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12419
分子式	C24H18N4O
分子量	378.43
CAS号	136194-77-9
SMILES	CN1C2=CC=CC=C2C3=C4C(=C5C6=CC=CC=C6N(C5=C31)CCC#N)CNC4=O
其他名称	Go6976, Go-6976
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 18 mg/mL (47.69 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC Na+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.42 mL	132.12 mL	264.25 mL
0.5 mM	5.28 mL	26.42 mL	52.85 mL
1 mM	2.64 mL	13.21 mL	26.42 mL
5 mM	0.53 mL	2.64 mL	5.28 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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