GRL0617
GRL0617 是一种强效、选择性且竞争性的非共价 SARS PLPro 抑制剂，其 IC50 为 0.6 μM，Ki 为 0.49 μM。
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生物活性
| Discription | GRL0617 is a potent, selective and competitive noncovalent inhibitor of SARS PLPro, with an IC50 of 0.6 μM, and with a Ki of 0.49 μM. | |||||
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| Cell Research |
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产品信息
| 目录号 | A18780 |
|---|---|
| 分子式 | C20H20N2O |
| 分子量 | 304.39 |
| CAS号 | 1093070-16-6 |
| SMILES | O=C(N[C@@H](C1=C2C=CC=CC2=CC=C1)C)C3=CC(N)=CC=C3C |
| 其他名称 | GRL 0617, GRL-0617 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 61 mg/mL (200.4 mM) | |
| Water | Insoluble | ||
| Ethanol | 21 mg/mL (68.99 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.85 mL | 164.26 mL | 328.53 mL |
| 0.5 mM | 6.57 mL | 32.85 mL | 65.71 mL |
| 1 mM | 3.29 mL | 16.43 mL | 32.85 mL |
| 5 mM | 0.66 mL | 3.29 mL | 6.57 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1093070-16-6 | 1093070-16-6 供应商 | 1093070-16-6 花费 | 1093070-16-6 生产商 | 订购 1093070-16-6 | 1093070-16-6 代理商