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GS-9451是一种新型的丙型肝炎病毒（HCV）非结构性3/4a（NS3/4a）蛋白酶抑制剂，在感染HCV基因型1（GT 1）的患者中具有很高的活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.98 mL | 54.91 mL | 109.83 mL |
| 0.5 mM | 2.2 mL | 10.98 mL | 21.97 mL |
| 1 mM | 1.1 mL | 5.49 mL | 10.98 mL |
| 5 mM | 0.22 mL | 1.1 mL | 2.2 mL |
*The above data is based on the productmolecular weight 910.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14046 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 910.52 |
| Formula | C45H60ClN7O9S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1310824-24-8 |
| Synonyms | GS 9451, GS9451 |
| SMILES | CC[C@@H]1C[C@@]1(C(=O)O)NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@H](C(C)(C)C)NC(=O)OC3C[C@H]4C[C@H]4C3)OC5=CC(=NC6=C5C=CC(=C6Cl)OCCN7CCOCC7)C8=CSC(=N8)NC(C)C |
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