Pemrametostat (GSK-3326595, EPZ015938)
目录号: A16862
PRMT5 抑制剂
GSK3326595 是一种强效、选择性、可逆的蛋白质精氨酸甲基转移酶5(PRMT5)抑制剂,其IC50为6.2 nM。
Discription | GSK3326595 is a potent, selective, reversible inhibitor of protein arginine methyltransferase 5 (PRMT5) with an IC50 of 6.2 nM. | |||||
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Cell Research |
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目录号 | A16862 |
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分子式 | C24H32N6O3 |
分子量 | 452.55 |
CAS号 | 1616392-22-3 |
SMILES | O=C(C)N1CCC(NC2=NC=NC(C(NC[C@H](O)CN3CCC(C=CC=C4)=C4C3)=O)=C2)CC1 |
其他名称 | GSK3326595, GSK 3326595, EPZ-015938, EPZ 015938 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 82 mg/mL (181.19 mM) | |
Water | Insoluble | ||
Ethanol | 82 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.1 mL | 110.49 mL | 220.97 mL |
0.5 mM | 4.42 mL | 22.1 mL | 44.19 mL |
1 mM | 2.21 mL | 11.05 mL | 22.1 mL |
5 mM | 0.44 mL | 2.21 mL | 4.42 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2