GSK221149A (Retosiban)
目录号: A13106
Oxytocin Receptor Ant激动剂
Retosiban(GSK-221,149-A)是一种口服药物,作为一种选择性的亚纳摩尔级(Ki = 0.65 nM)催产素受体拮抗剂,对相关的抗利尿激素受体具有超过1400倍的选择性。
Discription | Retosiban (GSK-221,149-A) is an oral drug which acts as a selective, sub-nanomolar (Ki = 0.65 nM) oxytocin receptor antagonist with >1400-fold selectivity[3] over the related vasopressin receptors |
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目录号 | A13106 |
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分子式 | C27H34N4O5 |
分子量 | 494.58 |
CAS号 | 820957-38-8 |
SMILES | CC[C@H](C)[C@@H]1C(=O)N[C@@H](C(=O)N1[C@H](C2=COC(=N2)C)C(=O)N3CCOCC3)C4CC5=CC=CC=C5C4 |
其他名称 | GSK-221149A, GSK 221149A |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2