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GSK2239633A is a CC-chemokine receptor 4 (CCR4) antagonist, which inhibits the binding of [125I]-TARC to human CCR4 with a pIC50 of 7.96????0.11.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.21 mL | 91.06 mL | 182.13 mL |
| 0.5 mM | 3.64 mL | 18.21 mL | 36.43 mL |
| 1 mM | 1.82 mL | 9.11 mL | 18.21 mL |
| 5 mM | 0.36 mL | 1.82 mL | 3.64 mL |
*The above data is based on the productmolecular weight 549.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12175 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 549.06 |
| Formula | C24H25ClN4O5S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1240516-71-5 |
| Synonyms | GSK 2239633A, GSK-2239633A |
| SMILES | CC(C)(O)C(NCC1=CC=CC(CN2N=C(NS(=O)(C3=CC=C(Cl)S3)=O)C4=C2C=CC=C4OC)=C1)=O |
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