GSK256066 2,2,2-trifluoroacetic acid

目录号: A15097
PDE Inhibitor
GSK256066 是一种选择性的 PDE4B(对A-D亚型具有相同的亲和力)抑制剂,其 IC50 为3.2 pM,对 PDE1/2/3/5/6 的选择性超过380,000倍,与 PDE7 相比对 PDE4B 的选择性超过2500倍。
Grouped product items
规格 价格 库存 数量
2mg
¥490.00
现货
5mg
¥665.00
现货
10mg
¥1,120.00
现货
50mg
¥3,780.00
现货
100mg
¥6,930.00
现货
500mg
¥11,865.00
现货
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生物活性
Discription GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.
产品信息
目录号 A15097
分子式 C29H27F3N4O7S
分子量 632.61
CAS号 1415560-64-3
SMILES CC1=C2C(=CC(=C1)S(=O)(=O)C3=CC=CC(=C3)C(=O)N(C)C)C(=C(C=N2)C(=O)N)NC4=CC(=CC=C4)OC.C(=O)(C(F)(F)F)O
其他名称 GSK-256066, GSK 256066
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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