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GSK2578215A

目录号: A12798
LRRK2 kinase 抑制剂
GSK2578215A 是一种强效的富含亮氨酸重复激酶 2(LRRK2)抑制剂(对于 LRRK2[G2019S] 突变体和野生型 LRRK2 的 IC50 值分别为 8.9 nM 和 10.1 nM)。
Grouped product items
规格 价格 库存 数量
5mg
¥140.00
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10mg
¥245.00
现货
25mg
¥525.00
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50mg
¥980.00
现货
100mg
¥1,610.00
现货
200mg
¥2,450.00
现货
10mM * 1mL in DMSO
¥140.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription GSK2578215A is a potent leucine-rich repeat kinase 2 (LRRK2) inhibitor (IC50 values are 8.9 and 10.1 nM respectively for LRRK2[G2019S] mutant and wild-type LRRK2 respectively).
Targets
Target Value
产品信息
目录号 A12798
分子式 C24H18FN3O2
分子量 399.42
CAS号 1285515-21-0
SMILES C1=CC=C(C=C1)COC2=C(C=C(C=C2)C3=CC(=NC=C3)F)C(=O)NC4=CN=CC=C4
其他名称 GSK-2578215A, GSK 2578215A
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO Warmed: 73 mg/mL (182.76 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.04 mL 125.18 mL 250.36 mL
0.5 mM 5.01 mL 25.04 mL 50.07 mL
1 mM 2.5 mL 12.52 mL 25.04 mL
5 mM 0.5 mL 2.5 mL 5.01 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

  • Calculator Reset
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