GSK2606414

Name: GSK2606414
SKU: A12792
Price: 385 CNY
Rating: 5 (3 reviews)

目录号: A12792

PERK 抑制剂

3 篇发表文献

GSK2606414 是一种口服可用的、高效的、选择性的 PERK 抑制剂，IC50 为 0.4 nM。

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Grouped product items
规格	价格	库存
2mg	¥385.00	现货
5mg	¥630.00	现货
10mg	¥840.00	现货
25mg	¥1,680.00	现货
50mg	¥2,660.00	现货
100mg	¥4,725.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用GSK2606414 发表的3篇文献

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Linhao Xu, .et al. , Neural Plasticity, 2021, 23 Aug

Takashi Shimizu, .et al. , Sci Signal, 2021, Jan 26;14(667):eabb3616 PMID: 33500333

生物活性

Discription

GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12792
分子式	C24H20F3N5O
分子量	451.44
CAS号	1337531-36-8
SMILES	CN1C=C(C2=C1N=CN=C2N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
其他名称	GSK-2606414, GSK 2606414
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	87 mg/mL (192.71 mM)
	Water	Insoluble
	Ethanol	18 mg/mL (39.87 mM)
In vivo	5% DMSO+45% PEG 300+ddH2O	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.15 mL	110.76 mL	221.51 mL
0.5 mM	4.43 mL	22.15 mL	44.3 mL
1 mM	2.22 mL	11.08 mL	22.15 mL
5 mM	0.44 mL	2.22 mL	4.43 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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