GSK2798745
目录号: A20799
TRPV4 ion channel blocker
GSK2798745 是一种首创的、高效的、选择性的、口服活性的瞬时受体电位钒4(TRPV4)离子通道阻断剂,其半抑制浓度(IC50)分别为1.8 nM和1.6 nM,针对人类TRPV4(hTRPV4)和大鼠TRPV4(rTRPV4)。
Discription | GSK2798745 is a first-in-class, highly potent, selective, orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker with IC50s of 1.8 and 1.6 nM for hTRPV4 and rTRPV4, respectively. |
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目录号 | A20799 |
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分子式 | C25H28N6O3 |
分子量 | 460.53 |
CAS号 | 1419609-94-1 |
SMILES | N#CC1=CC=C2N=CN(C[C@](CCC3)(C)C[C@@]43CN(C5=NC=C(C(C)(O)C)N=C5)C(O4)=O)C2=C1 |
其他名称 | GSK-2798745; GSK 2798745 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2