GSK3179106
目录号: A20434
RET kinase inhibitor
GSK3179106 是一种强效且选择性的 RET 激酶抑制剂，其 IC50 为 0.4 nM。
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生物活性
| Discription | GSK3179106 is a potent and selective RET kinase inhibitor with an IC50 of 0.4 nM. | |||||
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| Cell Research |
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产品信息
| 目录号 | A20434 |
|---|---|
| 分子式 | C22H21F4N3O4 |
| 分子量 | 467.41 |
| CAS号 | 1627856-64-7 |
| SMILES | O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)CC2=CC=C(C(C(OCC)=C3)=CNC3=O)C=C2F |
| 其他名称 | GSK 3179106, GSK-3179106 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 92 mg/mL (196.82 mM) | |
| Water | Insoluble | ||
| Ethanol | 6 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.39 mL | 106.97 mL | 213.94 mL |
| 0.5 mM | 4.28 mL | 21.39 mL | 42.79 mL |
| 1 mM | 2.14 mL | 10.7 mL | 21.39 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.28 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1627856-64-7 | 1627856-64-7 供应商 | 1627856-64-7 花费 | 1627856-64-7 生产商 | 订购 1627856-64-7 | 1627856-64-7 代理商