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GSK4112

产品详情

生物活性

GSK4112是选择性的Rev-erbα激动剂,EC50值为250 nM。GSK4112是小分子化学探针, 用于核血红素受体REV-erbα的细胞生物学研究。

溶解度 *

In vitro	DMSO	65 mg/mL (163.77 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (7.55 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.2 mL	125.98 mL	251.95 mL
0.5 mM	5.04 mL	25.2 mL	50.39 mL
1 mM	2.52 mL	12.6 mL	25.2 mL
5 mM	0.5 mL	2.52 mL	5.04 mL

*The above data is based on the productmolecular weight 396.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17135
作用机制	Agonist (激动剂)
M. Wt	396.9
Formula	C18H21ClN2O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1216744-19-2
Synonyms	GSK 4112, GSK-4112
SMILES	ClC(C=C1)=CC=C1CN(CC(OC(C)(C)C)=O)CC2=CC=C([N+]([O-])=O)S2