GSK484 hydrochloride
目录号: A12962
PAD4 抑制剂
GSK484 hydrochloride (GTPL8577) 是一种选择性和可逆的肽基精氨酸脱亚胺酶4(PAD4)抑制剂。
Discription | GSK484 hydrochloride (GTPL8577) is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. |
---|
目录号 | A12962 |
---|---|
分子式 | C27H32ClN5O3 |
分子量 | 510.03 |
CAS号 | 1652591-81-5 |
SMILES | O=C(N1C[C@H](N)[C@H](O)CC1)C2=CC(OC)=C3C(N=C(C(N4CC5CC5)=CC6=C4C=CC=C6)N3C)=C2.[H]Cl |
其他名称 | GSK 484,GSK-484, GTPL8577, GTPL-8577,GTPL 8577 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 92 mg/mL (180.38 mM) | |
Water | 7 mg/mL (13.72 mM) | ||
Ethanol | 92 mg/mL (180.38 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.61 mL | 98.03 mL | 196.07 mL |
0.5 mM | 3.92 mL | 19.61 mL | 39.21 mL |
1 mM | 1.96 mL | 9.8 mL | 19.61 mL |
5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2