Guadecitabine sodium
目录号: A21257
antineoplastic activity
Guadecitabine,也被称为SGI-110,是一种通过磷酸二酯键将去柠檬酸与鸟苷连接的二核苷酸抗代谢物,具有潜在的抗肿瘤活性。
Discription | Guadecitabine, aslo known as SGI-110, is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity. | ||
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Targets |
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目录号 | A21257 |
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分子式 | C18H23N9NaO10P |
分子量 | 579.39 |
CAS号 | 929904-85-8 |
SMILES | O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](COP(O[C@@H]4[C@@H](CO)O[C@@H](N5C=NC(N)=NC5=O)C4)([O-])=O)O3)C=N2)NC(N)=N1.[Na+] |
其他名称 | SGI-110 sodium; S-110 sodium |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 95 mg/mL (163.96 mM) | |
Water | 48 mg/mL (82.84 mM) | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.26 mL | 86.3 mL | 172.6 mL |
0.5 mM | 3.45 mL | 17.26 mL | 34.52 mL |
1 mM | 1.73 mL | 8.63 mL | 17.26 mL |
5 mM | 0.35 mL | 1.73 mL | 3.45 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2