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GW501516是一种合成pparδ特异性激动剂，对pparδ (ki=1.1 nm)显示出高亲和力，其选择性超过pparα和pparγ的1000倍。
| In vitro | DMSO | 86 mg/mL (189.63 mM) | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.05 mL | 110.25 mL | 220.51 mL |
| 0.5 mM | 4.41 mL | 22.05 mL | 44.1 mL |
| 1 mM | 2.21 mL | 11.03 mL | 22.05 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.41 mL |
*The above data is based on the productmolecular weight 453.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11437 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 453.5 |
| Formula | C21H18F3NO3S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 317318-70-0 |
| Synonyms | GW501516, GW-501516, GW1516, GSK-516, GW-1516, GSK516 |
| SMILES | CC1=C(C=CC(=C1)SCC2=C(N=C(S2)C3=CC=C(C=C3)C(F)(F)F)C)OCC(=O)O |
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