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GW3965 HCl是一种选择性的口服活性肝X受体（LXR）完全激动剂。
靶点信息
| hLXRβ (Cell-free assay) | LXRα/SRC1?LiSA (Cell-free assay) | hLXRα (Cell-free assay) | ||
| 30 nM(EC50) | 125 nM(EC50) | 190 nM(EC50) |
| In vitro | DMSO | Warmed: 16 mg/mL (25.86 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.17 mL | 80.84 mL | 161.68 mL |
| 0.5 mM | 3.23 mL | 16.17 mL | 32.34 mL |
| 1 mM | 1.62 mL | 8.08 mL | 16.17 mL |
| 5 mM | 0.32 mL | 1.62 mL | 3.23 mL |
*The above data is based on the productmolecular weight 618.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11204 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 618.51 |
| Formula | C33H31ClF3NO3.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 405911-17-3 |
| Synonyms | GW-3965 |
| SMILES | C1=CC=C(C=C1)C(CN(CCCOC2=CC=CC(=C2)CC(=O)O)CC3=C(C(=CC=C3)C(F)(F)F)Cl)C4=CC=CC=C4.Cl |
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