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GW4064

目录号: A11141
FXR 激动剂
GW4064 是一种选择性的、非甾体的法尼索特X受体(FXR)激动剂(EC50 = 15 nM)。
Grouped product items
规格 价格 库存 数量
5mg
¥280.00
现货
10mg
¥490.00
现货
25mg
¥945.00
现货
50mg
¥1,680.00
现货
100mg
¥3,080.00
现货
200mg
¥4,655.00
现货
500mg
¥7,385.00
现货
10mM * 1mL in DMSO
¥350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用GW4064发表的2篇文献
  • Dong-Hyun Kim, .et al. , Cell Death Dis, 2021, Apr; 12(4): 320 PMID: 33767132
  • Takae K, .et al. , J Reprod Dev, 2018, Nov 16 PMID: 30449821
  • 生物活性
    Discription GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
    Targets
    Target Value
    产品信息
    目录号 A11141
    分子式 C28H22Cl3NO4
    分子量 542.8
    CAS号 278779-30-9
    SMILES CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)/C=C/C4=CC(=CC=C4)C(=O)O)Cl
    其他名称 GW-4064
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 99 mg/mL (182.37 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% methylcellulose 10 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.42 mL 92.11 mL 184.23 mL
    0.5 mM 3.68 mL 18.42 mL 36.85 mL
    1 mM 1.84 mL 9.21 mL 18.42 mL
    5 mM 0.37 mL 1.84 mL 3.68 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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