GW806742X
目录号: A19569
MLKL inhibitor
GW806742X 是一种混合谱系激酶结构域样蛋白(MLKL)抑制剂,它与 MLKL 伪激酶结构域结合,结合常数(Kd)值为 9.3 微摩尔,并具有抗坏死性凋亡活性。GW806742X 对 VEGFR2 也具有活性。
Discription | GW806742X is a Mixed Lineage Kinase Domain-Like protein (MLKL) inhibitor which binds the MLKL pseudokinase domain with a Kd value of 9.3 μM and has anti-necroptosis activity. GW806742X has activity against VEGFR2. | |||||
---|---|---|---|---|---|---|
Targets |
|
|||||
Cell Research |
|
目录号 | A19569 |
---|---|
分子式 | C25H22F3N7O4S |
分子量 | 573.55 |
CAS号 | 579515-63-2 |
SMILES | O=S(C1=CC=CC(NC2=NC=CC(N(C)C3=CC=C(NC(NC4=CC=C(OC(F)(F)F)C=C4)=O)C=C3)=N2)=C1)(N)=O |
其他名称 | GW 806742X, GW-806742X |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2