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GW841819X是(+)-JQ1的类似物,是BET溴结构域的新型抑制剂。GW841819X是单个对映异构体,但在苯并二氮杂3.环3的4位具有不确定的手性。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.49 mL | 102.47 mL | 204.94 mL |
0.5 mM | 4.1 mL | 20.49 mL | 40.99 mL |
1 mM | 2.05 mL | 10.25 mL | 20.49 mL |
5 mM | 0.41 mL | 2.05 mL | 4.1 mL |
*The above data is based on the productmolecular weight 487.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A16367 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 487.94 |
Formula | C26H22ClN5O3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 146135-18-4 |
Synonyms | GW-841819X, GW 841819X |
SMILES | ClC(C=C1)=CC=C1C2=N[C@@H](NC(OCC3=CC=CC=C3)=O)C4=NN=C(C)N4C5=CC=C(OC)C=C52 |
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