微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
GZD824 Dimesylate是Bcr-Abl（WT）和Bcr-Abl（T315I）的新型生物可用Bcr-Abl抑制剂，IC50分别为0.34 nM和0.68 nM。
Targets
| Target | Value |
|---|---|
| Abl(Q252H) | IC50: 0.15nM |
| Abl(E255K) | IC50: 0.27nM |
| Abl(M351T) | IC50: 0.29nM |
| Abl | IC50: 0.34nM |
| Abl(H396P) | IC50: 0.35nM |
| Abl(Y253F) | IC50: 0.35nM |
| Abl(T315I) | IC50: 0.68nM |
| Abl(G250E) | IC50: 0.71nM |
| In vitro (25°C) | DMSO | 93 mg/mL (128.31 mM) | |
| Water | 93 mg/mL (128.31 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | Saline | 19 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.8 mL | 68.99 mL | 137.97 mL |
| 0.5 mM | 2.76 mL | 13.8 mL | 27.59 mL |
| 1 mM | 1.38 mL | 6.9 mL | 13.8 mL |
| 5 mM | 0.28 mL | 1.38 mL | 2.76 mL |
*The above data is based on the productmolecular weight 724.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15849 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 724.77 |
| Formula | C29H27F3N6O.2CH4O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1421783-64-3 |
| Synonyms | GZD-824 Dimesylate |
| SMILES | CC1=CC=C(C(NC2=CC=C(CN3CCN(C)CC3)C(C(F)(F)F)=C2)=O)C=C1C#CC4=CN=C5C(C=NN5)=C4.CS(=O)(O)=O.CS(=O)(O)=O |
产品标签
Product Questions
Product Questions
No Questions
Keywords:购买 GZD824 Dimesylate | GZD824 Dimesylate 供应商 | 订购 GZD824 Dimesylate | GZD824 Dimesylate 价格 | GZD824 Dimesylate 生产商 | 订单 GZD824 Dimesylate | GZD824 Dimesylate 代理商 | 购买 1421783-64-3| 1421783-64-3 供应商 | 订购 1421783-64-3 | 1421783-64-3 价格 | 1421783-64-3 生产商 | 订单 1421783-64-3 | 1421783-64-3 代理商|buy GZD824 Dimesylate | GZD824 Dimesylate Supplier | purchase GZD824 Dimesylate | GZD824 Dimesylate cost | GZD824 Dimesylate manufacturer | order GZD824 Dimesylate | GZD824 Dimesylate distributor | buy 1421783-64-3| 1421783-64-3 Supplier | purchase 1421783-64-3 | 1421783-64-3 cost | 1421783-64-3 manufacturer | order 1421783-64-3 | 1421783-64-3 distributor