GZD824 Dimesylate

Name: GZD824 Dimesylate
SKU: A15849
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A15849

Bcr-Abl 抑制剂

GZD824 是一种新型的口服生物利用度 Bcr-Abl 抑制剂，针对 Bcr-Abl(WT) 和 Bcr-Abl(T315I)，其 IC50 分别为 0.34 nM 和 0.68 nM。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥490.00	现货
10mg	¥805.00	现货
25mg	¥1,645.00	现货
50mg	¥2,310.00	现货
100mg	¥3,430.00	现货
*10mM 1mL in DMSO**	¥805.00	现货
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Data Sheet

SDS

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生物活性

Discription

GZD824 is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.

Targets

Target	Value

产品信息

目录号	A15849
分子式	C29H27F3N6O.2CH4O3S
分子量	724.77
CAS号	1421783-64-3
SMILES	CC1=CC=C(C(NC2=CC=C(CN3CCN(C)CC3)C(C(F)(F)F)=C2)=O)C=C1C#CC4=CN=C5C(C=NN5)=C4.CS(=O)(O)=O.CS(=O)(O)=O
其他名称	GZD-824 Dimesylate
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	93 mg/mL (128.31 mM)
	Water	93 mg/mL (128.31 mM)
	Ethanol	Insoluble
In vivo	Saline	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.8 mL	68.99 mL	137.97 mL
0.5 mM	2.76 mL	13.8 mL	27.59 mL
1 mM	1.38 mL	6.9 mL	13.8 mL
5 mM	0.28 mL	1.38 mL	2.76 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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