Harmaline
目录号: A17416
Harmaline 是一种在某些植物中自然存在的精神活性吲哚。它的刺激活性部分通过抑制单胺氧化酶实现,从而增加了单胺神经递质的水平(例如,在大鼠中为 7-70 μM/kg)。Harmaline(30 mg/kg)通过 N-甲基-D-天冬氨酸(NMDA)受体在小鼠中诱发震颤,Harmaline 可能作为该受体的反向激动剂。
Discription | Harmaline is a psychoactive indole found naturally in certain plants. Its stimulating activities are achieved, in part, through inhibition of monoamine oxidases, thus increasing the levels of monoamine neurotransmitters (e.g., at 7-70 μM/kg in rats). Harmaline (30 mg/kg) induces tremor in mice through the N-methyl-D-aspartate (NMDA) receptor, at which harmaline may act as an inverse agonist. |
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目录号 | A17416 |
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分子式 | C13H14N2O |
分子量 | 214.27 |
CAS号 | 304-21-2 |
SMILES | c12c3c([nH]c1C(=NCC2)C)cc(cc3)OC |
其他名称 | Harmaline |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 22 mg/mL (102.67 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 46.67 mL | 233.35 mL | 466.7 mL |
0.5 mM | 9.33 mL | 46.67 mL | 93.34 mL |
1 mM | 4.67 mL | 23.34 mL | 46.67 mL |
5 mM | 0.93 mL | 4.67 mL | 9.33 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2