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Hesperetin

目录号: A10449
PDE4 抑制剂
Hesperetin,一种选择性的磷酸二酯酶(PDE)4抑制剂,存在于传统中药陈皮中。Hesperetin 是一种柑橘类黄酮,已被报道可降低血浆胆固醇。Hesperetin 在剂量依赖性的方式下减少 Hep-G2 细胞中 ACAT-2 mRNA 的转录,并减少 ApoB 蛋白的合成。它也是一种潜在的类癌综合症癌症治疗方法。
Grouped product items
规格 价格 库存 数量
5mg
¥140.00
现货
10mg
¥210.00
现货
25mg
¥245.00
现货
50mg
¥350.00
现货
100mg
¥560.00
现货
10mM * 1mL in DMSO
¥315.00
现货
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生物活性
Discription Hesperetin, a selective phosphodiesterase (PDE)4 inhibitor, is present in the traditional Chinese medicine, ?€?Chen Pi.?€? Hesperetin is a citrus flavonoid that has been reported to lower plasma cholesterol. Hesperetin reduces the transcription of ACAT-2 mRNA in Hep-G2 cells and reduces ApoB protein synthesis in a dose-dependent manner. It also is a potential therapy for carcinoid cancer.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A10449
分子式 C16H14O6
分子量 302.3
CAS号 520-33-2
SMILES COC1=C(C=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O)O
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 58 mg/mL (191.87 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.08 mL 165.4 mL 330.8 mL
0.5 mM 6.62 mL 33.08 mL 66.16 mL
1 mM 3.31 mL 16.54 mL 33.08 mL
5 mM 0.66 mL 3.31 mL 6.62 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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