HG-9-91-01
目录号: A21004
SIK 抑制剂
HG-9-91-01 是一种高效且高度选择性的盐诱导激酶(SIK)抑制剂,其半抑制浓度(IC50)分别为 SIK1 0.92 nM、SIK2 6.6 nM 和 SIK3 9.6 nM。
Discription | HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIK) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively. |
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目录号 | A21004 |
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分子式 | C32H37N7O3 |
分子量 | 567.68 |
CAS号 | 1456858-58-4 |
SMILES | CC1=CC=CC(C)=C1NC(N(C2=NC=NC(NC3=CC=C(N4CCN(C)CC4)C=C3)=C2)C5=CC=C(OC)C=C5OC)=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 91 mg/mL (160.3 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.62 mL | 88.08 mL | 176.16 mL |
0.5 mM | 3.52 mL | 17.62 mL | 35.23 mL |
1 mM | 1.76 mL | 8.81 mL | 17.62 mL |
5 mM | 0.35 mL | 1.76 mL | 3.52 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2