HSP-990

Name: HSP-990
SKU: A12850

目录号: A12850

HSP90 抑制剂

Product Citations (1)

HSP-990 Chemical Structure

CAS NO. 934343-74-5

HSP990是人热休克蛋白90（Hsp90）的口服生物利用抑制剂，对HSP90α/β的IC50分别为0.6 nM和0.8 nM。具有潜在的抗肿瘤活性。

库存：现货

规格	价格	数量
5 mg	￥ 490.00
10 mg	￥ 840.00
25 mg	￥ 1,680.00
50 mg	￥ 2,800.00
10mM * 1mL in DMSO	￥ 784.00

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生物活性

HSP990是人热休克蛋白90（Hsp90）的口服生物利用抑制剂，对HSP90α/β的IC50分别为0.6 nM和0.8 nM。具有潜在的抗肿瘤活性。

靶点信息

HSP90α	HSP90β
0.6 nM	0.8 nM

溶解度 *

In vitro	DMSO	65 mg/mL (171.32 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.36 mL	131.79 mL	263.58 mL
0.5 mM	5.27 mL	26.36 mL	52.72 mL
1 mM	2.64 mL	13.18 mL	26.36 mL
5 mM	0.53 mL	2.64 mL	5.27 mL

*The above data is based on the productmolecular weight 379.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12850
作用机制	Inhibitor (抑制剂)
M. Wt	379.39
Formula	C20H18FN5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	934343-74-5
Synonyms	HSP990, HSP 990, NVP-HSP990
SMILES	CC1=NC(=NC2=C1C(=O)N[C@H](C2)C3=C(C=C(C=C3)F)C4=NC(=CC=C4)OC)N