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Hydroxychloroquine Sulfate是一种抗疟疾药，用于治疗系统性红斑狼疮，类风湿性关节炎和其他自身免疫性，炎性和皮肤病性疾病。还可以作为自噬和通行费样受体（TLR）7/9的抑制剂。
靶点信息
| TLR9 | Autophagy | |||
| In vitro | DMSO | Insoluble | |
| Water | 58 mg/mL (133.65 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.04 mL | 115.22 mL | 230.44 mL |
| 0.5 mM | 4.61 mL | 23.04 mL | 46.09 mL |
| 1 mM | 2.3 mL | 11.52 mL | 23.04 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.61 mL |
*The above data is based on the productmolecular weight 433.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14208 |
|---|---|
| M. Wt | 433.95 |
| Formula | C18H28ClN3O5S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 747-36-4 |
| SMILES | CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O |
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