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I-BET762 carboxylic acid

I-BET762 carboxylic acid

Name: I-BET762 carboxylic acid
SKU: A20149

目录号: A20149

BRD4 inhibitor

I-BET762 carboxylic acid Chemical Structure

CAS NO. 1300019-38-8

I-BET762 carboxylic acid (Molibresib carboxylic acid) is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1.

库存：现货

规格	价格	数量
1 mg	￥ 693.00
5 mg	￥ 2,079.00
10 mg	￥ 3,542.00
50 mg	￥ 10,626.00

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.2 mL	126 mL	252 mL
0.5 mM	5.04 mL	25.2 mL	50.4 mL
1 mM	2.52 mL	12.6 mL	25.2 mL
5 mM	0.5 mL	2.52 mL	5.04 mL

*The above data is based on the productmolecular weight 396.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20149
M. Wt	396.83
Formula	C20H17ClN4O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1300019-38-8
Synonyms	Molibresib carboxylic acid; GSK525762A carboxylic acid, GSK 525762A, GSK-525762A; PROTAC BRD4-binding moiety 2; IBET762, I-BET 762, I-BET-762
SMILES	CC1=NN=C2[C@H](CC(O)=O)N=C(C3=CC=C(Cl)C=C3)C4=C(C=CC(OC)=C4)N21