I-BET762 carboxylic acid
目录号: A20149
BRD4 抑制剂
I-BET762 羧酸(Molibresib 羧酸)是基于 I-BET762 的战斗部位配体,用于针对 BET 的 PROTAC 结合反应。I-BET762 羧酸(Molibresib 羧酸)是一种 BRD4 抑制剂,具有 pIC50 值为 5.1。
Discription | I-BET762 carboxylic acid (Molibresib carboxylic acid) is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1. | ||
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目录号 | A20149 |
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分子式 | C20H17ClN4O3 |
分子量 | 396.83 |
CAS号 | 1300019-38-8 |
SMILES | CC1=NN=C2[C@H](CC(O)=O)N=C(C3=CC=C(Cl)C=C3)C4=C(C=CC(OC)=C4)N21 |
其他名称 | Molibresib carboxylic acid; GSK525762A carboxylic acid, GSK 525762A, GSK-525762A; PROTAC BRD4-binding moiety 2; IBET762, I-BET 762, I-BET-762 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2