IACS-8968 S-enantiomer
目录号: A21559
dual IDO/TDO 抑制剂
IACS-8968 (S-对映体) 是 IACS-8968 的 S-对映体。IACS-8968 是一种双重 IDO 和 TDO 抑制剂,其对 IDO 的 pIC50 为 6.43,对 TDO 的 pIC50 小于 5。
Discription | IACS-8968 (S-enantiomer) is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively. |
---|
目录号 | A21559 |
---|---|
分子式 | C17H18F3N5O2 |
分子量 | 381.35 |
CAS号 | 2239305-70-3 |
SMILES | O=C(N1)N[C@@]2(C(C)(C)CN(C3=CC(C(F)(F)F)=CC4=CN=CN34)CC2)C1=O |
其他名称 | IDO/TDO Inhibitor (S-enantiomer), IACS8968, IACS 8968 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2