IAXO-102

Name: IAXO-102
SKU: A18543
Price: 560 CNY
Rating: 5 (288 reviews)

目录号: A18543

TLR4 拮抗剂

IAXO-102 是一种 TLR4 拮抗剂，能够负向调节 TLR4 信号传导。它抑制 MAPK 和 p65 NF-κB 的磷酸化，并抑制 TLR4 依赖的促炎症蛋白的表达。

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Grouped product items
规格	价格	库存
1mg	¥560.00	现货
2mg	¥910.00	现货
5mg	¥1,785.00	现货
10mg	¥2,905.00	现货
25mg	¥4,760.00	现货
50mg	¥6,825.00	现货
100mg	¥9,415.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. It inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein.

Targets

Target	Value

产品信息

目录号	A18543
分子式	C35H71NO5
分子量	585.94
CAS号	1115270-63-7
SMILES	CCCCCCCCCCCCCCO[C@@H]1[C@H]([C@@H]([C@@H](CN)O[C@@H]1OC)O)OCCCCCCCCCCCCCC
其他名称	IAXO102, IAXO 102
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	13 mg/mL (22.18 mM)
	Water	Insoluble
	Ethanol	85 mg/mL (145.06 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.07 mL	85.33 mL	170.67 mL
0.5 mM	3.41 mL	17.07 mL	34.13 mL
1 mM	1.71 mL	8.53 mL	17.07 mL
5 mM	0.34 mL	1.71 mL	3.41 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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