Ibiglustat
目录号: A21083
GCS 抑制剂
Ibiglustat(Venglustat),一种针对帕金森病(PD)、法布里病(Fabry's)和高雪氏病(Gaucher's)的潜在疗法,是一种选择性的、变构抑制剂,针对葡萄糖神经酰胺合成酶(GCS),具有穿越血脑屏障的能力。
Discription | Ibiglustat (Venglustat), a potential therapy for PD Parkinson??s disease, SRT in Fabry??s and Gaucher??s, is a selective, allosteric inhibitor of glucosylceramide synthase (GCS) with ability to cross the blood-brain barrier. |
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目录号 | A21083 |
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分子式 | C20H24FN3O2S |
分子量 | 389.49 |
CAS号 | 1401090-53-6 |
SMILES | O=C(O[C@@H]1CN2CCC1CC2)NC(C)(C3=CSC(C4=CC=C(F)C=C4)=N3)C |
其他名称 | Venglustat; SAR402671, SAR 402671, SAR-402671; GZ402671, GZ 402671, GZ-402671 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2