IC-87114

Name: IC-87114
SKU: A10463
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A10463

PI3K 抑制剂

IC-87114 是首个异构体选择性的 PI3K 抑制剂：p110M-NM-4（IC50 = 0.13 M-BM-5M）相比于 p110M-NM-1（IC50 = 200 M-BM-5M）、p110M-NM-2（IC50 = 16 M-BM-5M）和 p110M-NM-3（IC50 = 61 M-BM-5M）。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥525.00	现货
25mg	¥980.00	现货
50mg	¥1,715.00	现货
100mg	¥2,730.00	现货
200mg	¥4,025.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription

IC-87114 was the first isoform-selective PI3K inhibitor :p110M-NM-4(IC50 = 0.13 M-BM-5M) vs. p110M-NM-1(IC50 = 200 M-BM-5M), p110M-NM-2(IC50 = 16 M-BM-5M) and p110M-NM-3(IC50 = 61 M-BM-5M).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10463
分子式	C22H19N7O
分子量	397.4
CAS号	371242-69-2
SMILES	CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C=NC5=C4N=CN=C5N
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	0.62 mg/mL (1.56 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+30% PEG 300+ddH2O	0.6 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.16 mL	125.82 mL	251.64 mL
0.5 mM	5.03 mL	25.16 mL	50.33 mL
1 mM	2.52 mL	12.58 mL	25.16 mL
5 mM	0.5 mL	2.52 mL	5.03 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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