Icariin
目录号: A10464
PDE5 抑制剂
Icariin 对所有三种 PDE5 异构体具有抑制作用,分别抑制 PDE5A1、A2 和 A3,其 IC50 值分别为 1.0、0.75 和 1.1 微摩尔。
Discription | Icariin is inhibitory to all three PDE5 isoforms that inhibits PDE5A1, A2, and A3 with an IC50 value of 1.0, 0.75, and 1.1 microM, respectively. | |||||
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Targets |
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Cell Research |
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目录号 | A10464 |
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分子式 | C33H40O15 |
分子量 | 676.7 |
CAS号 | 489-32-7 |
SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 46 mg/mL (67.98 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 14.78 mL | 73.89 mL | 147.78 mL |
0.5 mM | 2.96 mL | 14.78 mL | 29.56 mL |
1 mM | 1.48 mL | 7.39 mL | 14.78 mL |
5 mM | 0.3 mL | 1.48 mL | 2.96 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2