ICEC0942 HCl

Name: ICEC0942 HCl
SKU: A16903

目录号: A16903

CDK7 抑制剂

ICEC0942 HCl Chemical Structure

CAS NO. 1805789-54-1

ICEC0942 HCl，也称为CT7001，是CDK7的口服生物利用选择性抑制剂。它选择性抑制CDK7，IC50为40nM。CDK1，CDK2，CDK5和CDK9的IC50值分别高45倍，15倍，230倍和30倍。

库存：现货

规格	价格	数量
5 mg	￥ 2,240.00
10 mg	￥ 3,640.00
50 mg	￥ 11,200.00
100 mg	￥ 17,500.00

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生物活性

ICEC0942 HCl，也称为CT7001，是CDK7的口服生物利用选择性抑制剂。它选择性抑制CDK7，IC50为40nM。CDK1，CDK2，CDK5和CDK9的IC50值分别高45倍，15倍，230倍和30倍。

溶解度 *

In vitro	DMSO	76 mg/mL (176.34 mM)
	Water	76 mg/mL (176.34 mM)
	Ethanol	13 mg/mL (30.16 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.2 mL	116.01 mL	232.03 mL
0.5 mM	4.64 mL	23.2 mL	46.41 mL
1 mM	2.32 mL	11.6 mL	23.2 mL
5 mM	0.46 mL	2.32 mL	4.64 mL

*The above data is based on the productmolecular weight 430.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16903
作用机制	Inhibitor (抑制剂)
M. Wt	430.98
Formula	C22H31ClN6O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1805789-54-1
Synonyms	CT7001
SMILES	O[C@H]1CNCC[C@@H]1CNC2=NC3=C(C(C)C)C=NN3C(NCC4=CC=CC=C4)=C2.[H]Cl