ICEC0942 HCl

Name: ICEC0942 HCl
SKU: A16903
Price: 770 CNY
Rating: 5 (288 reviews)

目录号: A16903

CDK7 inhibitor

ICEC0942，亦称为CT7001，是一种用于癌症治疗的口服生物可利用的选择性CDK7抑制剂。它选择性地抑制CDK7，其IC50为40nM；对CDK1、CDK2、CDK5和CDK9的IC50值分别高出45倍、15倍、230倍和30倍。

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Grouped product items
规格	价格	库存
1mg	¥770.00	现货
5mg	¥1,680.00	现货
10mg	¥2,730.00	现货
25mg	¥4,585.00	现货
50mg	¥6,545.00	现货
100mg	¥8,925.00	现货
*10mM 1mL in DMSO**	¥1,855.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

ICEC0942, also known as CT7001, is an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment. It selectively inhibits CDK7, with an IC50 of 40nM; IC50 values for CDK1, CDK2, CDK5 and CDK9 were 45-, 15-, 230- and 30-fold higher.

Targets

Target	Value

产品信息

目录号	A16903
分子式	C22H31ClN6O
分子量	430.98
CAS号	1805789-54-1
SMILES	O[C@H]1CNCC[C@@H]1CNC2=NC3=C(C(C)C)C=NN3C(NCC4=CC=CC=C4)=C2.[H]Cl
其他名称	CT7001
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	76 mg/mL (176.34 mM)
	Water	76 mg/mL (176.34 mM)
	Ethanol	13 mg/mL (30.16 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.2 mL	116.01 mL	232.03 mL
0.5 mM	4.64 mL	23.2 mL	46.41 mL
1 mM	2.32 mL	11.6 mL	23.2 mL
5 mM	0.46 mL	2.32 mL	4.64 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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