ICG-001

Name: ICG-001
SKU: A11039
Price: 175 CNY
Rating: 5 (8 reviews)

目录号: A11039

Wnt/beta-catenin 抑制剂

8 篇发表文献

ICG-001 是一种特定的 Wnt/β-catenin 信号通路抑制剂，它抑制 β-catenin/环状AMP反应元件结合（CREB）蛋白转录（IC50=3 微米）。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥385.00	现货
10mg	¥665.00	现货
25mg	¥1,470.00	现货
50mg	¥2,590.00	现货
100mg	¥3,815.00	现货
500mg	¥8,785.00	现货
*10mM 1mL in DMSO**	¥490.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用ICG-001 发表的8篇文献

Hong Gao, .et al. , Sci Rep, 2024, Oct 15;14(1):24182 PMID: 39406776

Yun-Sheng Chen, .et al. , Research Square, 2024, August 16th

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Seonmin Choi, .et al. , Yonsei Med J, 2021, Nov;62(11):1042-1051 PMID: 34672138

Jasper C.Munro, .et al. , Livest Sci, 2019, 229 (2019) 159-169

Kim JH, .et al. , Cell Rep, 2019, May 14;27(7):2105-2118.e5 PMID: 31091449

Yamaoka R, .et al. , J Surg Oncol, 2018, Sep;118(4):664-674 PMID: 30196535

Aida Y, .et al. , In Vitro Cell Dev Biol Anim, 2018, Jun;54(6):468-476 PMID: 29785536

生物活性

Discription

ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11039
分子式	C33H32N4O4
分子量	548.6
CAS号	780757-88-2, 847591-62-2
SMILES	C1CN([C@H]2CN(C(=O)[C@@H](N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6
其他名称	ICG001
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	99 mg/mL (180.45 mM)
	Water	Insoluble
	Ethanol	10 mg/mL
In vivo	2% DMSO+50% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.23 mL	91.14 mL	182.28 mL
0.5 mM	3.65 mL	18.23 mL	36.46 mL
1 mM	1.82 mL	9.11 mL	18.23 mL
5 mM	0.36 mL	1.82 mL	3.65 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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