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Icilin

目录号: A13560
TRPM8 and TRPA1 activator
Icilin 是一种冷却剂,它激活了新型冷感受器 TRPM8 (CMR1)TRPA1 (ANKTM1/TRPN1),这两者都是 TRP 离子通道家族 的成员。在表达 CMR1 的 HEK 293 细胞中诱导电流(EC50 = 0.36 μM)
Grouped product items
规格 价格 库存 数量
5mg
¥175.00
现货
10mg
¥315.00
现货
25mg
¥630.00
现货
50mg
¥1,225.00
现货
100mg
¥2,135.00
现货
500mg
¥9,240.00
现货
10mM * 1mL in DMSO
¥175.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Icilin is a cooling agent that activates the novel cold receptors TRPM8 (CMR1) and TRPA1 (ANKTM1/TRPN1), members of the TRP ion channel family. Induces currents in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM)
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A13560
分子式 C16H13N3O4
分子量 311.3
CAS号 36945-98-9
SMILES C1C=C(NC(=O)N1C2=CC=CC=C2O)C3=CC(=CC=C3)[N+](=O)[O-]
其他名称 AG 3-5
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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