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Idarubicin HCl是蒽环类抗生素，是一种比柔红霉素具有更高DNA结合能力和更大细胞毒性的抗白血病药物。
靶点信息
| Topo II (MCF-7 cells) (Cell-free assay) | Multicellular spheroids (Cell-free assay) | |||
| 3.3 ng/mL | 7.9 ng/mL |
| In vitro | DMSO | 88 mg/mL (164.81 mM) | |
| Water | Warmed: 4 mg/mL (7.49 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.73 mL | 93.63 mL | 187.27 mL |
| 0.5 mM | 3.75 mL | 18.73 mL | 37.45 mL |
| 1 mM | 1.87 mL | 9.36 mL | 18.73 mL |
| 5 mM | 0.37 mL | 1.87 mL | 3.75 mL |
*The above data is based on the productmolecular weight 534. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10465 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 534 |
| Formula | C26H28ClNO9 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 57852-57-0 |
| Synonyms | Idamycin, Zavedos, 4-demethoxydaunorubicin, DMDR, IMI-30 |
| SMILES | C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl |
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