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DH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.6 mL | 123.01 mL | 246.01 mL |
| 0.5 mM | 4.92 mL | 24.6 mL | 49.2 mL |
| 1 mM | 2.46 mL | 12.3 mL | 24.6 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
*The above data is based on the productmolecular weight 406.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18420 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 406.48 |
| Formula | C26H22N4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2244895-42-7 |
| SMILES | N#CC1=C[C@@]2(C3=CC=CC=C3)[C@](CCC4=C2N=C(NC5=CC=CC=C5)N=C4)([H])[C@H](C)C1=O |
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