Iguratimod (T 614)

Name: Iguratimod (T 614)
SKU: A11464
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A11464

COX-2 抑制剂

Iguratimod(T 614) 是一系列4H-1-苯并吡喃-4-酮中的一种，具有强大的抗炎、镇痛和解热活性。Iguratimod(T 614) 是环氧合酶-2（COX-2）的选择性抑制剂，并抑制白细胞介素-1（IL-1）、IL-6、IL-8 和肿瘤坏死因子的产生。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥385.00	现货
25mg	¥735.00	现货
50mg	¥1,400.00	现货
100mg	¥1,820.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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Data Sheet

SDS

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生物活性

Discription

Iguratimod(T 614) is one of a series of 4H-1-benzopyran-4-ones which has potent anti-inflammatory, analgesic and antipyretic activity. Iguratimod(T 614) is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor.

Targets

Target	Value

产品信息

目录号	A11464
分子式	C17H14N2O6S
分子量	374.37
CAS号	123663-49-0
SMILES	CS(=O)(=O)NC1=C(C=C2C(=C1)OC=C(C2=O)NC=O)OC3=CC=CC=C3
其他名称	T614
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	46 mg/mL (122.87 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.71 mL	133.56 mL	267.12 mL
0.5 mM	5.34 mL	26.71 mL	53.42 mL
1 mM	2.67 mL	13.36 mL	26.71 mL
5 mM	0.53 mL	2.67 mL	5.34 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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