产品详情
IKK 16是针对IKK-2,IKK复合物和IKK-1的选择性IκB激酶(IKK)抑制剂,IC50分别为40 nM,70 nM和200 nM。
靶点信息
IKK2 (Cell-free assay) | IKK complex (Cell-free assay) | IKK1 (Cell-free assay) | ||
40 nM | 70 nM | 200 nM |
In vitro (25°C) | DMSO | 95 mg/mL (196.42 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.68 mL | 103.38 mL | 206.77 mL |
0.5 mM | 4.14 mL | 20.68 mL | 41.35 mL |
1 mM | 2.07 mL | 10.34 mL | 20.68 mL |
5 mM | 0.41 mL | 2.07 mL | 4.14 mL |
*The above data is based on the productmolecular weight 483.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A12836 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 483.63 |
Formula | C28H29N5OS |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 873225-46-8 |
Synonyms | IKK 16, IKK16 |
SMILES | C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5 |
产品标签
Product Questions
Product Questions
No Questions
Keywords:购买 IKK-16 | IKK-16 供应商 | 订购 IKK-16 | IKK-16 价格 | IKK-16 生产商 | 订单 IKK-16 | IKK-16 代理商 | 购买 873225-46-8| 873225-46-8 供应商 | 订购 873225-46-8 | 873225-46-8 价格 | 873225-46-8 生产商 | 订单 873225-46-8 | 873225-46-8 代理商|buy IKK-16 | IKK-16 Supplier | purchase IKK-16 | IKK-16 cost | IKK-16 manufacturer | order IKK-16 | IKK-16 distributor | buy 873225-46-8| 873225-46-8 Supplier | purchase 873225-46-8 | 873225-46-8 cost | 873225-46-8 manufacturer | order 873225-46-8 | 873225-46-8 distributor