IM-12

Name: IM-12
SKU: A14196
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A14196

GSK-3β 抑制剂

IM-12 是一种可渗透细胞的吲哚马来酰亚胺，作为糖原合成酶激酶3β (GSK-3β) 抑制剂，激活下游的经典Wnt信号传导组分。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥385.00	现货
25mg	¥805.00	现货
50mg	¥1,365.00	现货
100mg	¥2,415.00	现货
500mg	¥7,595.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

IM-12 is a cell-permeable indolylmaleimide that acts as a Glycogen synthase kinase 3β (GSK-3β) inhibitor, activating downstream components of canonical Wnt signaling.

Targets

Target	Value

产品信息

目录号	A14196
分子式	C22H20FN3O2
分子量	377.41
CAS号	1129669-05-1
SMILES	CC1=C(C2=CC=CC=C2N1)C3=C(C(=O)N(C3=O)C)NCCC4=CC=C(C=C4)F
其他名称	IM12, IM 12
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	72 mg/mL (190.77 mM)
	Water	Insoluble
	Ethanol	Warmed: 10 mg/mL (26.49 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.5 mL	132.48 mL	264.96 mL
0.5 mM	5.3 mL	26.5 mL	52.99 mL
1 mM	2.65 mL	13.25 mL	26.5 mL
5 mM	0.53 mL	2.65 mL	5.3 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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