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IMD 0354

目录号: A12837
IKK 抑制剂
IMD 0354 是一种抑制剂,针对 IκB激酶-β (IKKβ),能够阻断 NF-κB 核内转移。
Grouped product items
规格 价格 库存 数量
2mg
¥245.00
现货
5mg
¥385.00
现货
10mg
¥525.00
现货
25mg
¥1,015.00
现货
50mg
¥1,435.00
现货
100mg
¥2,240.00
现货
500mg
¥5,495.00
现货
10mM * 1mL in DMSO
¥385.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用IMD 0354发表的1篇文献
  • Anton Lennikov, .et al. , Angiogenesis, 2018, 21(2): 267-285 PMID: 29332242
  • 生物活性
    Discription IMD 0354 is an inhibitor of IκB kinase-β (IKKβ) that blocks NF-κB nuclear translocation.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A12837
    分子式 C15H8ClF6NO2
    分子量 383.67
    CAS号 978-62-1
    SMILES C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)O
    其他名称 IMD-0354, IMD0354
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 9 mg/mL (23.45 mM)
    Water Insoluble
    Ethanol 72 mg/mL (187.66 mM)
    In vivo 2% DMSO+5% Tween 80+0.5% CMC Na 2 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.06 mL 130.32 mL 260.64 mL
    0.5 mM 5.21 mL 26.06 mL 52.13 mL
    1 mM 2.61 mL 13.03 mL 26.06 mL
    5 mM 0.52 mL 2.61 mL 5.21 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

    • Calculator Reset
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