Importazole
目录号: A17128
nuclear transport receptor importin-β 抑制剂
Importazole 是一种能够渗透细胞的 importin-β 抑制剂。它通过改变 importin-β 与 RanGTP 的相互作用，特异性地抑制 importin-β 的功能。
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生物活性
| Discription | Importazole is a cell-permeable inhibitor of importin-β. It specifically inhibits the function of importin-β, likely by altering its interaction with RanGTP. |
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产品信息
| 目录号 | A17128 |
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| 分子式 | C20H22N4 |
| 分子量 | 318.4 |
| CAS号 | 662163-81-7 |
| SMILES | [H]N(C(C1=CC=CC=C1)C)C2=NC(N3CCCC3)=NC4=C2C=CC=C4 |
| 其他名称 | IPZ |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 58 mg/mL (182.15 mM) | |
| Water | Insoluble | ||
| Ethanol | 29 mg/mL (91.07 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.41 mL | 157.04 mL | 314.07 mL |
| 0.5 mM | 6.28 mL | 31.41 mL | 62.81 mL |
| 1 mM | 3.14 mL | 15.7 mL | 31.41 mL |
| 5 mM | 0.63 mL | 3.14 mL | 6.28 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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