Inauhzin
目录号: A12527
SIRT1 抑制剂
Inauhzin 是一种强效的 SIRT 抑制剂，通过抑制 SIRT1 活性有效地重新激活 p53，促进依赖 p53 的人类癌细胞凋亡，而不会显著引起基因毒性应激。
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生物活性
| Discription | Inauhzin is a potent SIRT inhibitor, which effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human cancer cells without causing apparently genotoxic stress. | ||
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产品信息
| 目录号 | A12527 |
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| 分子式 | C25H19N5OS2 |
| 分子量 | 469.58 |
| CAS号 | 309271-94-1 |
| SMILES | CCC(C(=O)N1C2=CC=CC=C2SC3=CC=CC=C31)SC4=NC5=C(C6=CC=CC=C6N5)N=N4 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 82 mg/mL (174.62 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.3 mL | 106.48 mL | 212.96 mL |
| 0.5 mM | 4.26 mL | 21.3 mL | 42.59 mL |
| 1 mM | 2.13 mL | 10.65 mL | 21.3 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.26 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 309271-94-1 | 309271-94-1 供应商 | 309271-94-1 花费 | 309271-94-1 生产商 | 订购 309271-94-1 | 309271-94-1 代理商