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INCB3344

目录号: A11465
CCR2 拮抗剂
INCB3344 是一种效力强大、选择性高且可口服的 CCR2 拮抗剂,其在结合拮抗作用中的 IC50 值分别为 5.1 nM (hCCR2) 和 9.5 nM (mCCR2),在化学趋化活性拮抗中的 IC50 值分别为 3.8 nM (hCCR2) 和 7.8 nM (mCCR2)。
Grouped product items
规格 价格 库存 数量
1mg
¥385.00
现货
5mg
¥1,015.00
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10mg
¥1,715.00
现货
25mg
¥2,975.00
现货
50mg
¥4,305.00
现货
100mg
¥6,265.00
现货
10mM * 1mL in DMSO
¥1,330.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
Targets
Target Value
产品信息
目录号 A11465
分子式 C29H34F3N3O6
分子量 577.59
CAS号 1262238-11-8
SMILES CCO[C@H]1CN([C@]2([H])CC[C@@](CC2)(C3=CC4=C(OCO4)C=C3)O)C[C@@H]1NC(CNC(C5=CC(C(F)(F)F)=CC=C5)=O)=O
其他名称 INCB 3344, INCB-3344
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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