Incyclinide

Name: Incyclinide
SKU: A17240
Price: 525 CNY
Rating: 5 (288 reviews)

目录号: A17240

MMP 抑制剂

Iincyclinide，也被称为 CMT-3 和 COL-3，是一种 MMP 抑制剂 和具有潜在抗肿瘤活性的化学修饰四环素。Iincyclinide 抑制基质金属蛋白酶（MMPs），从而诱导细胞外基质降解，并抑制血管生成、肿瘤生长和侵袭以及转移。此药物还会导致肿瘤细胞的线粒体去极化，并诱导细胞凋亡和组织坏死。

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Grouped product items
规格	价格	库存
1mg	¥525.00	现货
5mg	¥805.00	现货
10mg	¥1,330.00	现货
25mg	¥2,940.00	现货
50mg	¥4,480.00	现货
100mg	¥6,405.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription

Iincyclinide, also known as CMT-3 and COL-3, is a MMP inhibitor and a chemically-modified tetracycline with potential antineoplastic activity. Incyclinide inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. This agent also causes mitochondrial depolarization in tumor cells and induces both cellular apoptosis and tissue necrosis.

产品信息

目录号	A17240
分子式	C19H17NO7
分子量	371.34
CAS号	15866-90-7
SMILES	O=C(C1=C(O)C[C@@](C[C@@]2([H])C(C(C3=C(O)C=CC=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N
其他名称	CMT-3; CMT 3; CMT3; COL3; COL-3; COL 3
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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