Indomethacin (Indocid, Indocin)

Name: Indomethacin (Indocid, Indocin)
SKU: A10474
Price: 175 CNY
Rating: 5 (3 reviews)

目录号: A10474

COX 抑制剂

3 篇发表文献

Indomethacin 是一种非选择性 COX1 和 COX2 抑制剂，其 IC50 分别为 0.1 µg/mL 和 5 µg/mL。Indomethacin（商品名为 Indocid、Indocin）是一种非甾体抗炎药，常用于减少发烧、疼痛、僵硬和肿胀。

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Grouped product items
规格	价格	库存
100mg	¥175.00	现货
500mg	¥280.00	现货
1g	¥315.00	现货
5g	¥735.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Indomethacin (Indocid, Indocin)发表的3篇文献

Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967

Azuma T, .et al. , Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504

Azuma T, .et al. , Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

生物活性

Discription

Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10474
分子式	C19H16ClNO4
分子量	357.79
CAS号	53-86-1
SMILES	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O
其他名称	Indomethacin, Indochron E-R, Indocin-SR, Indocid
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	63 mg/mL (176.08 mM)
	Water	Insoluble
	Ethanol	21 mg/mL (58.69 mM)
In vivo	5% DMSO+30% PEG 300+5% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.95 mL	139.75 mL	279.49 mL
0.5 mM	5.59 mL	27.95 mL	55.9 mL
1 mM	2.79 mL	13.97 mL	27.95 mL
5 mM	0.56 mL	2.79 mL	5.59 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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