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IPI-493是一种有效且口服可生物利用的HSP90抑制剂，Ki为21 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.33 mL | 91.64 mL | 183.28 mL |
| 0.5 mM | 3.67 mL | 18.33 mL | 36.66 mL |
| 1 mM | 1.83 mL | 9.16 mL | 18.33 mL |
| 5 mM | 0.37 mL | 1.83 mL | 3.67 mL |
*The above data is based on the productmolecular weight 545.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11272 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 545.62 |
| Formula | C28H39N3O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 64202-81-9 |
| Synonyms | IPI493; IPI 493; NSC 255109;17-Aminogeldanamycin;17-Amino Geldanamycin;17-Aminodemethoxygeldanamycin;17-Amino-17-demethoxygeldanamycin; |
| SMILES | C[C@H]1C[C@H]([C@H]([C@@H](/C=C(/[C@H]([C@@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)N)/C)OC)OC(=O)N)\C)C)O)OC |
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