Irinotecan HCl Trihydrate (Campto)

Name: Irinotecan HCl Trihydrate (Campto)
SKU: A10479
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A10479

Topoisomerase 抑制剂

1 篇发表文献

伊立替康（CPT 11），一种来源于喜树碱家族的化合物，是拓扑异构酶 1的抑制剂，参与细胞 DNA 的复制和转录。

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Grouped product items
规格	价格	库存
25mg	¥210.00	现货
50mg	¥315.00	现货
100mg	¥455.00	现货
200mg	¥630.00	现货
500mg	¥1,085.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Irinotecan HCl Trihydrate (Campto)发表的1篇文献

Jingyao Gan, .et al. , Int J Pharm, 2025, Jan 25:669:125000 PMID: 39608586

生物活性

Discription

Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of topoisomerase 1 involved in cellular DNA replication and transcription.

Targets

Target	Value

产品信息

目录号	A10479
分子式	C33H38N4O6.HCl.3H2O
分子量	677.2
CAS号	136572-09-3
SMILES	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl
其他名称	CPT 11, Camptosar
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	92 mg/mL (135.86 mM)
	Water	1 mg/mL (1.47 mM)
	Ethanol	6 mg/mL (8.85 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.77 mL	73.83 mL	147.67 mL
0.5 mM	2.95 mL	14.77 mL	29.53 mL
1 mM	1.48 mL	7.38 mL	14.77 mL
5 mM	0.3 mL	1.48 mL	2.95 mL

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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