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Irinotecan HCl Trihydrate (Campto)

Irinotecan HCl Trihydrate (Campto)

Name: Irinotecan HCl Trihydrate (Campto)
SKU: A10479

目录号: A10479

Topoisomerase 抑制剂

Irinotecan HCl Trihydrate (Campto) Chemical Structure

CAS NO. 136572-09-3

Irinotecan (CPT 11)是喜树碱家族的一种化合物，是参与细胞DNA复制和转录的拓扑异构酶1的抑制剂。

库存：现货

规格	价格	数量
200 mg	￥ 350.00
10mM * 1mL in DMSO	￥ 427.00

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生物活性

Irinotecan (CPT 11)是喜树碱家族的一种化合物，是参与细胞DNA复制和转录的拓扑异构酶1的抑制剂。

靶点信息

Topo I

溶解度 *

In vitro	DMSO	92 mg/mL (135.86 mM)
	Water	1 mg/mL (1.47 mM)
	Ethanol	6 mg/mL (8.85 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.77 mL	73.83 mL	147.67 mL
0.5 mM	2.95 mL	14.77 mL	29.53 mL
1 mM	1.48 mL	7.38 mL	14.77 mL
5 mM	0.3 mL	1.48 mL	2.95 mL

*The above data is based on the productmolecular weight 677.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10479
作用机制	Inhibitor (抑制剂)
M. Wt	677.2
Formula	C33H38N4O6.HCl.3H2O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	136572-09-3
Synonyms	CPT 11, Camptosar, Campto, Irinotecan
SMILES	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7.O.O.O.Cl