Irinotecan

Name: Irinotecan
SKU: A10478
Price: 140 CNY
Rating: 5 (2 reviews)

目录号: A10478

Topoisomerase I 抑制剂

2 篇发表文献

伊立替康通过抑制拓扑异构酶1，阻止DNA解旋。

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Grouped product items
规格	价格	库存
10mg	¥140.00	现货
25mg	¥245.00	现货
50mg	¥350.00	现货
100mg	¥385.00	现货
200mg	¥665.00	现货
500mg	¥1,540.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Irinotecan发表的2篇文献

Gils Jose, .et al. , Cancers (Basel), 2020, Oct 31;12(11):E3211 PMID: 33142721

T Kannathasan, .et al. , Cancers (Basel), 2020, May; 12(5): 1231 PMID: 32422901

生物活性

Discription

Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10478
分子式	C33H38N4O6
分子量	586.7
CAS号	97682-44-5
SMILES	CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
其他名称	Camptosar, CPT-11
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	6 mg/mL (10.23 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.04 mL	85.22 mL	170.44 mL
0.5 mM	3.41 mL	17.04 mL	34.09 mL
1 mM	1.7 mL	8.52 mL	17.04 mL
5 mM	0.34 mL	1.7 mL	3.41 mL

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