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IRL-2500是一种有效的选择性ETBR拮抗剂。它显示了对ETB受体的一些选择性(对于ETB和ETA受体,IC50值分别为1.3和94 nM)。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.43 mL | 87.16 mL | 174.31 mL |
0.5 mM | 3.49 mL | 17.43 mL | 34.86 mL |
1 mM | 1.74 mL | 8.72 mL | 17.43 mL |
5 mM | 0.35 mL | 1.74 mL | 3.49 mL |
*The above data is based on the productmolecular weight 573.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13638 |
---|---|
作用机制 | Antagonist (拮抗剂) |
M. Wt | 573.68 |
Formula | C36H35N3O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 169545-27-1 |
Synonyms | IRL2500, IRL 2500 |
SMILES | CC1=CC(=CC(=C1)C(=O)N(C)[C@H](CC2=CC=C(C=C2)C3=CC=CC=C3)C(=O)N[C@@H](CC4=CNC5=CC=CC=C54)C(=O)O)C |
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