Ispinesib (SB-715992)

Name: Ispinesib (SB-715992)
SKU: A10486

目录号: A10486

KSP 抑制剂

Ispinesib (SB-715992) Chemical Structure

CAS NO. 336113-53-2

Ispinesib (SB-715992)是驱动蛋白纺锤体蛋白的有效抑制剂，驱动蛋白纺锤体蛋白是双极有丝分裂纺锤体形成和有丝分裂细胞周期进程所必需的驱动蛋白。

库存：现货

规格	价格	数量
5 mg	￥ 630.00
10 mg	￥ 1,120.00
50 mg	￥ 3,360.00
100 mg	￥ 5,600.00
10mM * 1mL in DMSO	￥ 1,498.00

或

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产品详情

生物活性

Ispinesib (SB-715992)是驱动蛋白纺锤体蛋白的有效抑制剂，驱动蛋白纺锤体蛋白是双极有丝分裂纺锤体形成和有丝分裂细胞周期进程所必需的驱动蛋白。

靶点信息

KSP (HsEg5) (Cell-free assay)
1.7 nM(Ki app)

溶解度 *

In vitro	DMSO	93 mg/mL (179.86 mM)
	Water	Insoluble
	Ethanol	93 mg/mL (179.86 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.34 mL	96.69 mL	193.39 mL
0.5 mM	3.87 mL	19.34 mL	38.68 mL
1 mM	1.93 mL	9.67 mL	19.34 mL
5 mM	0.39 mL	1.93 mL	3.87 mL

*The above data is based on the productmolecular weight 517.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10486
作用机制	Inhibitor (抑制剂)
M. Wt	517.1
Formula	C30H33ClN4O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	336113-53-2
Synonyms	Ispinesib mesylate,B-715992,CK 0238273
SMILES	CC1=CC=C(C=C1)C(=O)N(CCCN)[C@@H](C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C